There are phase 1-3 trials for a very promising drug and roche has now taken over the trial. Plexxikon was the original manufacture and now genentech and roche are performing the clinical trials. It is rumored that positive results can be known in days and there are no side efffects. If you or anyone you know is suffering with stage 4 Melanoma have them contact the Melanoma Research Foundation for more info.
www.melanoma.org
Here is a link to the official clinical trials info:
clinicaltrials.gov/ct2/show/NCT00405587